BDBM50324785 (3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(6-oxopyridazin-1(6H)-yl)phenyl)-1-(methylsulfonyl)pyrrolidine-3,4-dicarboxamide::CHEMBL1222285

SMILES: CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ncccc1=O)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=WPUDWYBGCRVIAB-ROUUACIJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50324785 ((3R,4R)-N3-(4-chlorophenyl)-N4-(2-fluoro-4-(6-oxop...) Show SMILES CS(=O)(=O)N1C[C@@H]([C@H](C1)C(=O)Nc1ccc(cc1F)-n1ncccc1=O)C(=O)Nc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H21ClFN5O5S/c1-36(34,35)29-12-17(22(32)27-15-6-4-14(24)5-7-15)18(13-29)23(33)28-20-9-8-16(11-19(20)25)30-21(31)3-2-10-26-30/h2-11,17-18H,12-13H2,1H3,(H,27,32)(H,28,33)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to factor 10a				Bioorg Med Chem Lett 20: 5313-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.126 BindingDB Entry DOI: 10.7270/Q2542NSG
					More data for this Ligand-Target Pair