BDBM50324863 CHEMBL1222363::Naphthalene-2-sulfonic acid [3-(4-methyl-piperazin-1-yl)-phenyl]-propyl-amide

SMILES: CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key: InChIKey=XJHVIMRPUTXKEU-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50324863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from human 5HT2C expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2 expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50324863 (CHEMBL1222363 | Naphthalene-2-sulfonic acid [3-(4-...) Show SMILES CCCN(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H29N3O2S/c1-3-13-27(23-10-6-9-22(19-23)26-16-14-25(2)15-17-26)30(28,29)24-12-11-20-7-4-5-8-21(20)18-24/h4-12,18-19H,3,13-17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A expressed in CHOKI cells				Bioorg Med Chem Lett 20: 5221-4 (2010) Article DOI: 10.1016/j.bmcl.2010.06.150 BindingDB Entry DOI: 10.7270/Q27W6CCH
					More data for this Ligand-Target Pair