BDBM50324894 CHEMBL1221594::N-(6-(4-(2-methoxyphenyl)piperazin-1-yl)hexyl)naphthalene-2-sulfonamide

SMILES: COc1ccccc1N1CCN(CCCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1

InChI Key: InChIKey=WEXLHWFGOZCTNY-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50324894 (CHEMBL1221594 | N-(6-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H35N3O3S/c1-33-27-13-7-6-12-26(27)30-20-18-29(19-21-30)17-9-3-2-8-16-28-34(31,32)25-15-14-23-10-4-5-11-24(23)22-25/h4-7,10-15,22,28H,2-3,8-9,16-21H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]MK912 from human alpha2A receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50324894 (CHEMBL1221594 | N-(6-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H35N3O3S/c1-33-27-13-7-6-12-26(27)30-20-18-29(19-21-30)17-9-3-2-8-16-28-34(31,32)25-15-14-23-10-4-5-11-24(23)22-25/h4-7,10-15,22,28H,2-3,8-9,16-21H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from human 5HT1A receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50324894 (CHEMBL1221594 | N-(6-(4-(2-methoxyphenyl)piperazin...) Show SMILES COc1ccccc1N1CCN(CCCCCCNS(=O)(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H35N3O3S/c1-33-27-13-7-6-12-26(27)30-20-18-29(19-21-30)17-9-3-2-8-16-28-34(31,32)25-15-14-23-10-4-5-11-24(23)22-25/h4-7,10-15,22,28H,2-3,8-9,16-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Liège Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2L receptor after 60 mins				Bioorg Med Chem Lett 20: 5199-202 (2010) Article DOI: 10.1016/j.bmcl.2010.07.002 BindingDB Entry DOI: 10.7270/Q2445MPJ
					More data for this Ligand-Target Pair