BDBM50324900 3-(pyridin-4-yl)imidazo[1,2-a]pyrimidine::CHEMBL1221924

SMILES: c1nc2ncccn2c1-c1ccncc1

InChI Key: InChIKey=GUXIYQWCRMHBNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50324900 (3-(pyridin-4-yl)imidazo[1,2-a]pyrimidine | CHEMBL1...) Show SMILES c1nc2ncccn2c1-c1ccncc1 Show InChI InChI=1S/C11H8N4/c1-4-13-11-14-8-10(15(11)7-1)9-2-5-12-6-3-9/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+6	n/a	n/a	n/a	n/a	n/a	n/a
Evotec UK Ltd Curated by ChEMBL					Assay Description Inhibition of BACE1 assessed as amyloid beta secretion by cell based assay				Bioorg Med Chem Lett 20: 5329-33 (2010) Article DOI: 10.1016/j.bmcl.2010.06.089 BindingDB Entry DOI: 10.7270/Q2VQ32W7
					More data for this Ligand-Target Pair