BDBM50324904 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-isopropylbutanamide::CHEMBL1221978

SMILES: CC(C)NC(=O)CCCn1c(N)nc2cc(Cl)ccc12

InChI Key: InChIKey=DODYWTFDGHLEGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50324904 (4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-is...) Show SMILES CC(C)NC(=O)CCCn1c(N)nc2cc(Cl)ccc12 Show InChI InChI=1S/C14H19ClN4O/c1-9(2)17-13(20)4-3-7-19-12-6-5-10(15)8-11(12)18-14(19)16/h5-6,8-9H,3-4,7H2,1-2H3,(H2,16,18)(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
Evotec UK Ltd Curated by ChEMBL					Assay Description Inhibition of BACE1 assessed as amyloid beta secretion by cell based assay				Bioorg Med Chem Lett 20: 5329-33 (2010) Article DOI: 10.1016/j.bmcl.2010.06.089 BindingDB Entry DOI: 10.7270/Q2VQ32W7
					More data for this Ligand-Target Pair