BDBM50324908 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)butanamide::CHEMBL1222031

SMILES: Nc1nc2cc(Cl)ccc2n1CCCC(=O)NCC1CCCCC1

InChI Key: InChIKey=JHBRHRSPHWUPGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50324908 (4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(c...) Show SMILES Nc1nc2cc(Cl)ccc2n1CCCC(=O)NCC1CCCCC1 Show InChI InChI=1S/C18H25ClN4O/c19-14-8-9-16-15(11-14)22-18(20)23(16)10-4-7-17(24)21-12-13-5-2-1-3-6-13/h8-9,11,13H,1-7,10,12H2,(H2,20,22)(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Evotec UK Ltd Curated by ChEMBL					Assay Description Inhibition of BACE1 assessed as amyloid beta secretion by cell based assay				Bioorg Med Chem Lett 20: 5329-33 (2010) Article DOI: 10.1016/j.bmcl.2010.06.089 BindingDB Entry DOI: 10.7270/Q2VQ32W7
					More data for this Ligand-Target Pair