BDBM50324916 (R)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-isopropyl-5-methylhexanamide::CHEMBL1222143

SMILES: CC(C)C[C@H](CC(=O)NC(C)C)n1c(N)nc2cc(Cl)ccc12

InChI Key: InChIKey=MQBQMYOSDZAGET-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50324916 ((R)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-...) Show SMILES CC(C)C[C@H](CC(=O)NC(C)C)n1c(N)nc2cc(Cl)ccc12 |r| Show InChI InChI=1S/C17H25ClN4O/c1-10(2)7-13(9-16(23)20-11(3)4)22-15-6-5-12(18)8-14(15)21-17(22)19/h5-6,8,10-11,13H,7,9H2,1-4H3,(H2,19,21)(H,20,23)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Evotec UK Ltd Curated by ChEMBL					Assay Description Inhibition of BACE1 assessed as amyloid beta secretion by cell based assay				Bioorg Med Chem Lett 20: 5329-33 (2010) Article DOI: 10.1016/j.bmcl.2010.06.089 BindingDB Entry DOI: 10.7270/Q2VQ32W7
					More data for this Ligand-Target Pair