BDBM50324995 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4'-(trifluoromethyl)biphenyl-4-yl)imidazolidine-2,4-dione::CHEMBL1222802

SMILES: Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)C(F)(F)F)C(=O)c2c1

InChI Key: InChIKey=QZJSMMIDRSHMNT-DEOSSOPVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50324995 ((R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4...) Show SMILES Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)C(F)(F)F)C(=O)c2c1 |r| Show InChI InChI=1S/C25H17F4N3O3/c26-19-10-5-16-12-32(21(33)20(16)11-19)13-24(22(34)30-23(35)31-24)17-6-1-14(2-7-17)15-3-8-18(9-4-15)25(27,28)29/h1-11H,12-13H2,(H2,30,31,34,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE assessed as inhibition of pro-TNFalpha peptide cleavage				Bioorg Med Chem Lett 20: 5286-9 (2010) Article DOI: 10.1016/j.bmcl.2010.06.134 BindingDB Entry DOI: 10.7270/Q26W9B8K
					More data for this Ligand-Target Pair