BDBM50325057 1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl)-4-((tetrahydrofuran-2-yl)methyl)piperazine::CHEMBL1223011

SMILES: Fc1ccc(cc1)C(N1CCN(CC2CCCO2)CC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=KMTSJTZWICQBLS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325057 (1-((1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)meth...) Show SMILES Fc1ccc(cc1)C(N1CCN(CC2CCCO2)CC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C24H29FN6O/c25-21-10-8-20(9-11-21)23(24-26-27-28-31(24)17-19-5-2-1-3-6-19)30-14-12-29(13-15-30)18-22-7-4-16-32-22/h1-3,5-6,8-11,22-23H,4,7,12-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair