BDBM50325090 1-((1-benzyl-1H-tetrazol-5-yl)(4-(2-methyl-1H-imidazol-1-yl)phenyl)methyl)-4-cyclobutyl-1,4-diazepane::CHEMBL1222499

SMILES: Cc1nccn1-c1ccc(cc1)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=JJFDWPWNEGCWAO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325090 (1-((1-benzyl-1H-tetrazol-5-yl)(4-(2-methyl-1H-imid...) Show SMILES Cc1nccn1-c1ccc(cc1)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C28H34N8/c1-22-29-15-18-35(22)26-13-11-24(12-14-26)27(34-17-6-16-33(19-20-34)25-9-5-10-25)28-30-31-32-36(28)21-23-7-3-2-4-8-23/h2-4,7-8,11-15,18,25,27H,5-6,9-10,16-17,19-21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair