BDBM50325100 5-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-diazepan-1-yl)methyl)-1-methyl-1H-indole::CHEMBL1222663

SMILES: Cn1ccc2cc(ccc12)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1

InChI Key: InChIKey=BDEYAIBDEBYGLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50325100 (5-((1-benzyl-1H-tetrazol-5-yl)(4-cyclobutyl-1,4-di...) Show SMILES Cn1ccc2cc(ccc12)C(N1CCCN(CC1)C1CCC1)c1nnnn1Cc1ccccc1 Show InChI InChI=1S/C27H33N7/c1-31-16-13-22-19-23(11-12-25(22)31)26(33-15-6-14-32(17-18-33)24-9-5-10-24)27-28-29-30-34(27)20-21-7-3-2-4-8-21/h2-4,7-8,11-13,16,19,24,26H,5-6,9-10,14-15,17-18,20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Bioorg Med Chem Lett 20: 5165-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.009 BindingDB Entry DOI: 10.7270/Q2TQ61RV
					More data for this Ligand-Target Pair