BDBM50325144 5-methyl-8-(1H-pyrrol-3-yl)-[1,2,4]triazolo[4,3-a]quinolin-1(2H)-one::CHEMBL1223527

SMILES: Cc1cc2n[nH]c(=O)n2c2cc(ccc12)-c1cc[nH]c1

InChI Key: InChIKey=VRNWPXZMRNCCLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50325144 (5-methyl-8-(1H-pyrrol-3-yl)-[1,2,4]triazolo[4,3-a]...) Show SMILES Cc1cc2n[nH]c(=O)n2c2cc(ccc12)-c1cc[nH]c1 Show InChI InChI=1S/C15H12N4O/c1-9-6-14-17-18-15(20)19(14)13-7-10(2-3-12(9)13)11-4-5-16-8-11/h2-8,16H,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of His6-CHK1 expressed in baculovirus infected Sf9 cells				Bioorg Med Chem Lett 20: 5133-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.015 BindingDB Entry DOI: 10.7270/Q2FF3SJZ
					More data for this Ligand-Target Pair				3D Structure (docked)