BDBM50325362 (R)-N-(3-(5-(1-cyclohexyl-2-(methylamino)-2-oxoethylcarbamoyl)furan-2-yl)benzyl)-8-methylimidazo[1,2-a]pyridine-2-carboxamide::CHEMBL1223057

SMILES: CNC(=O)[C@H](NC(=O)c1ccc(o1)-c1cccc(CNC(=O)c2cn3cccc(C)c3n2)c1)C1CCCCC1

InChI Key: InChIKey=KMPABSMQUVIRLC-AREMUKBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50325362 ((R)-N-(3-(5-(1-cyclohexyl-2-(methylamino)-2-oxoeth...) Show SMILES CNC(=O)[C@H](NC(=O)c1ccc(o1)-c1cccc(CNC(=O)c2cn3cccc(C)c3n2)c1)C1CCCCC1 |r| Show InChI InChI=1S/C30H33N5O4/c1-19-8-7-15-35-18-23(33-27(19)35)28(36)32-17-20-9-6-12-22(16-20)24-13-14-25(39-24)29(37)34-26(30(38)31-2)21-10-4-3-5-11-21/h6-9,12-16,18,21,26H,3-5,10-11,17H2,1-2H3,(H,31,38)(H,32,36)(H,34,37)/t26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 20: 5039-43 (2010) Article DOI: 10.1016/j.bmcl.2010.07.036 BindingDB Entry DOI: 10.7270/Q28S4Q3K
					More data for this Ligand-Target Pair