BDBM50325363 (R)-5-(3-(acetamidomethyl)phenyl)-N-(1-cyclohexyl-2-(methylamino)-2-oxoethyl)furan-2-carboxamide::CHEMBL1222989
SMILES: CNC(=O)[C@H](NC(=O)c1ccc(o1)-c1cccc(CNC(C)=O)c1)C1CCCCC1
InChI Key: InChIKey=CEVYCPKDAIYJCG-OAQYLSRUSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collagenase 3 (Homo sapiens (Human)) | BDBM50325363 ((R)-5-(3-(acetamidomethyl)phenyl)-N-(1-cyclohexyl-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of MMP13 | Bioorg Med Chem Lett 20: 5039-43 (2010) Article DOI: 10.1016/j.bmcl.2010.07.036 BindingDB Entry DOI: 10.7270/Q28S4Q3K | |||||||||||
More data for this Ligand-Target Pair |