BDBM50325434 (R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)-4-methylpentanamide::CHEMBL1222413

SMILES: CC(C)C[C@@H](N)C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl

InChI Key: InChIKey=RADQDLRYXIUSGX-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50325434 ((R)-2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinol...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl |r| Show InChI InChI=1S/C15H18ClN3O2/c1-8(2)5-12(17)15(21)19-13-6-9-3-4-18-14(20)10(9)7-11(13)16/h3-4,6-8,12H,5,17H2,1-2H3,(H,18,20)(H,19,21)/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 5153-6 (2010) Article DOI: 10.1016/j.bmcl.2010.07.014 BindingDB Entry DOI: 10.7270/Q2RR1ZDC
					More data for this Ligand-Target Pair