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BDBM50325483 (4-cyclohexylpiperazin-1-yl)(1-(pyridin-4-ylmethyl)piperidin-4-yl)methanone::CHEMBL1222419

SMILES: O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(CC1)C1CCCCC1

InChI Key: InChIKey=MAKZZEYOURRWCV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325483   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325483
PNG
((4-cyclohexylpiperazin-1-yl)(1-(pyridin-4-ylmethyl...)
Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C22H34N4O/c27-22(26-16-14-25(15-17-26)21-4-2-1-3-5-21)20-8-12-24(13-9-20)18-19-6-10-23-11-7-19/h6-7,10-11,20-21H,1-5,8-9,12-18H2
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 14n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair