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BDBM50325487 CHEMBL1223220::N-(3-methoxypropyl)-3-((4-(1-(pyridin-4-ylmethyl)piperidine-4-carbonyl)piperazin-1-yl)methyl)benzamide

SMILES: COCCCNC(=O)c1cccc(CN2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1

InChI Key: InChIKey=QSAOZDKFQFDNNG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HRH3


(GUINEA PIG)		BDBM50325487
PNG
(CHEMBL1223220 | N-(3-methoxypropyl)-3-((4-(1-(pyri...)
Show SMILES COCCCNC(=O)c1cccc(CN2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1
Show InChI InChI=1S/C28H39N5O3/c1-36-19-3-10-30-27(34)26-5-2-4-24(20-26)22-32-15-17-33(18-16-32)28(35)25-8-13-31(14-9-25)21-23-6-11-29-12-7-23/h2,4-7,11-12,20,25H,3,8-10,13-19,21-22H2,1H3,(H,30,34)
UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 210n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair