BDBM50325512 4-bromo-5-ethyl-2-(4-isopropylphenyl)-7-methoxy-1-(2-methoxyethyl)-1H-benzo[d]imidazole::CHEMBL1222424

SMILES: CCc1cc(OC)c2n(CCOC)c(nc2c1Br)-c1ccc(cc1)C(C)C

InChI Key: InChIKey=WTLMRENAAYANIL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325512 (4-bromo-5-ethyl-2-(4-isopropylphenyl)-7-methoxy-1-...) Show SMILES CCc1cc(OC)c2n(CCOC)c(nc2c1Br)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C22H27BrN2O2/c1-6-15-13-18(27-5)21-20(19(15)23)24-22(25(21)11-12-26-4)17-9-7-16(8-10-17)14(2)3/h7-10,13-14H,6,11-12H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
					More data for this Ligand-Target Pair