BDBM50325632 (7-fluoro-1H-indol-5-yl)(2-propylpyrrolidin-2-yl)methanone::CHEMBL1224165
SMILES: CCCC1(CCCN1)C(=O)c1cc(F)c2[nH]ccc2c1
InChI Key: InChIKey=WTCFDFPSNBMAOR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50325632 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50325632
((7-fluoro-1H-indol-5-yl)(2-propylpyrrolidin-2-yl)m...)Show InChI InChI=1S/C16H19FN2O/c1-2-5-16(6-3-7-19-16)15(20)12-9-11-4-8-18-14(11)13(17)10-12/h4,8-10,18-19H,2-3,5-7H2,1H3 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020
BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50325632
((7-fluoro-1H-indol-5-yl)(2-propylpyrrolidin-2-yl)m...)Show InChI InChI=1S/C16H19FN2O/c1-2-5-16(6-3-7-19-16)15(20)12-9-11-4-8-18-14(11)13(17)10-12/h4,8-10,18-19H,2-3,5-7H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020
BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this
Ligand-Target Pair | |
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