BDBM50325634 (4-amino-3-chlorophenyl)(2-propylpyrrolidin-2-yl)methanone::CHEMBL1224089
SMILES: CCCC1(CCCN1)C(=O)c1ccc(N)c(Cl)c1
InChI Key: InChIKey=WVZMHYCNWMCWBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50325634 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50325634
((4-amino-3-chlorophenyl)(2-propylpyrrolidin-2-yl)m...)Show InChI InChI=1S/C14H19ClN2O/c1-2-6-14(7-3-8-17-14)13(18)10-4-5-12(16)11(15)9-10/h4-5,9,17H,2-3,6-8,16H2,1H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020 BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50325634
((4-amino-3-chlorophenyl)(2-propylpyrrolidin-2-yl)m...)Show InChI InChI=1S/C14H19ClN2O/c1-2-6-14(7-3-8-17-14)13(18)10-4-5-12(16)11(15)9-10/h4-5,9,17H,2-3,6-8,16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020 BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this Ligand-Target Pair | |