BDBM50325637 (1H-indazol-5-yl)(2-isobutylpyrrolidin-2-yl)methanone::CHEMBL1224093
SMILES: CC(C)CC1(CCCN1)C(=O)c1ccc2[nH]ncc2c1
InChI Key: InChIKey=HXVMFBSINMZKRO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50325637 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50325637
((1H-indazol-5-yl)(2-isobutylpyrrolidin-2-yl)methan...)Show InChI InChI=1S/C16H21N3O/c1-11(2)9-16(6-3-7-17-16)15(20)12-4-5-14-13(8-12)10-18-19-14/h4-5,8,10-11,17H,3,6-7,9H2,1-2H3,(H,18,19) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020 BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50325637
((1H-indazol-5-yl)(2-isobutylpyrrolidin-2-yl)methan...)Show InChI InChI=1S/C16H21N3O/c1-11(2)9-16(6-3-7-17-16)15(20)12-4-5-14-13(8-12)10-18-19-14/h4-5,8,10-11,17H,3,6-7,9H2,1-2H3,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020 BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this Ligand-Target Pair | |