BDBM50325638 (2-(3,3-dimethylbutyl)pyrrolidin-2-yl)(1H-indazol-5-yl)methanone::CHEMBL1224094
SMILES: CC(C)(C)CCC1(CCCN1)C(=O)c1ccc2[nH]ncc2c1
InChI Key: InChIKey=WMONHIUXMOXBDS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50325638 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50325638
((2-(3,3-dimethylbutyl)pyrrolidin-2-yl)(1H-indazol-...)Show InChI InChI=1S/C18H25N3O/c1-17(2,3)8-9-18(7-4-10-19-18)16(22)13-5-6-15-14(11-13)12-20-21-15/h5-6,11-12,19H,4,7-10H2,1-3H3,(H,20,21) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020
BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50325638
((2-(3,3-dimethylbutyl)pyrrolidin-2-yl)(1H-indazol-...)Show InChI InChI=1S/C18H25N3O/c1-17(2,3)8-9-18(7-4-10-19-18)16(22)13-5-6-15-14(11-13)12-20-21-15/h5-6,11-12,19H,4,7-10H2,1-3H3,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto LLC
Curated by ChEMBL
| Assay Description
Inhibition of human ERG |
Bioorg Med Chem Lett 20: 5559-66 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.020
BindingDB Entry DOI: 10.7270/Q20865HF |
More data for this
Ligand-Target Pair | |
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