BDBM50325726 (R)-N-(2-chlorobenzyl)-1-(3-methoxyphenyl)ethanamine::CHEMBL1224191

SMILES: COc1cccc(c1)[C@@H](C)NCc1ccccc1Cl

InChI Key: InChIKey=PRLUQJLALYHTLK-GFCCVEGCSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325726 ((R)-N-(2-chlorobenzyl)-1-(3-methoxyphenyl)ethanami...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccccc1Cl |r| Show InChI InChI=1S/C16H18ClNO/c1-12(13-7-5-8-15(10-13)19-2)18-11-14-6-3-4-9-16(14)17/h3-10,12,18H,11H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325726 ((R)-N-(2-chlorobenzyl)-1-(3-methoxyphenyl)ethanami...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccccc1Cl |r| Show InChI InChI=1S/C16H18ClNO/c1-12(13-7-5-8-15(10-13)19-2)18-11-14-6-3-4-9-16(14)17/h3-10,12,18H,11H2,1-2H3/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair