BDBM50325729 (R)-N-((2'-fluorobiphenyl-3-yl)methyl)-1-(3-methoxyphenyl)ethanamine::CHEMBL1224260

SMILES: COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1F

InChI Key: InChIKey=AKNXCVXQUJVRHZ-MRXNPFEDSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325729 ((R)-N-((2'-fluorobiphenyl-3-yl)methyl)-1-(3-methox...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1F |r| Show InChI InChI=1S/C22H22FNO/c1-16(18-8-6-10-20(14-18)25-2)24-15-17-7-5-9-19(13-17)21-11-3-4-12-22(21)23/h3-14,16,24H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50325729 ((R)-N-((2'-fluorobiphenyl-3-yl)methyl)-1-(3-methox...) Show SMILES COc1cccc(c1)[C@@H](C)NCc1cccc(c1)-c1ccccc1F |r| Show InChI InChI=1S/C22H22FNO/c1-16(18-8-6-10-20(14-18)25-2)24-15-17-7-5-9-19(13-17)21-11-3-4-12-22(21)23/h3-14,16,24H,15H2,1-2H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calcium				Bioorg Med Chem Lett 20: 5544-7 (2010) Article DOI: 10.1016/j.bmcl.2010.07.060 BindingDB Entry DOI: 10.7270/Q2Z89CM3
					More data for this Ligand-Target Pair