BDBM50325771 5-methyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL1224270

SMILES: Cc1cc(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O

InChI Key: InChIKey=YYQZSSDDXSNFOR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50325771 (5-methyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H...) Show SMILES Cc1cc(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O Show InChI InChI=1S/C18H14F3N3O2/c1-11-9-15(17(22)25)23-24(11)13-6-4-5-12(10-13)14-7-2-3-8-16(14)26-18(19,20)21/h2-10H,1H3,(H2,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 by VIPR assay				Bioorg Med Chem Lett 20: 7479-82 (2010) Article DOI: 10.1016/j.bmcl.2010.10.017 BindingDB Entry DOI: 10.7270/Q2MW2HDH
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50325771 (5-methyl-1-(2'-(trifluoromethoxy)biphenyl-3-yl)-1H...) Show SMILES Cc1cc(nn1-c1cccc(c1)-c1ccccc1OC(F)(F)F)C(N)=O Show InChI InChI=1S/C18H14F3N3O2/c1-11-9-15(17(22)25)23-24(11)13-6-4-5-12(10-13)14-7-2-3-8-16(14)26-18(19,20)21/h2-10H,1H3,(H2,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Nav 1.7 channel by voltage-ion-probe-reader				Bioorg Med Chem Lett 20: 5480-3 (2010) Article DOI: 10.1016/j.bmcl.2010.07.080 BindingDB Entry DOI: 10.7270/Q2PV6KJX
					More data for this Ligand-Target Pair