BDBM50325926 2-(2-o-Tolyl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL1224221

SMILES: Cc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1

InChI Key: InChIKey=CBZXOMYALABZPC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50325926 (2-(2-o-Tolyl-ethoxymethyl)-3H-pyrido[2,3-d]pyrimid...) Show SMILES Cc1ccccc1CCOCc1nc2ncccc2c(=O)[nH]1 Show InChI InChI=1S/C17H17N3O2/c1-12-5-2-3-6-13(12)8-10-22-11-15-19-16-14(17(21)20-15)7-4-9-18-16/h2-7,9H,8,10-11H2,1H3,(H,18,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of radioligand from human GPR109A				Bioorg Med Chem Lett 20: 5426-30 (2010) Article DOI: 10.1016/j.bmcl.2010.07.108 BindingDB Entry DOI: 10.7270/Q2NV9JGF
					More data for this Ligand-Target Pair