BDBM50325978 CHEMBL1224387::ethyl 4-(1-(4-(1-(4-fluorophenyl)-1H-benzo[d]imidazol-2-yl)butyl)piperidin-4-yl)-2-hydroxybenzoate

SMILES: CCOC(=O)c1ccc(cc1O)C1CCN(CCCCc2nc3ccccc3n2-c2ccc(F)cc2)CC1

InChI Key: InChIKey=CYYGNFHTNGYTMY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50325978 (CHEMBL1224387 | ethyl 4-(1-(4-(1-(4-fluorophenyl)-...) Show SMILES CCOC(=O)c1ccc(cc1O)C1CCN(CCCCc2nc3ccccc3n2-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C31H34FN3O3/c1-2-38-31(37)26-15-10-23(21-29(26)36)22-16-19-34(20-17-22)18-6-5-9-30-33-27-7-3-4-8-28(27)35(30)25-13-11-24(32)12-14-25/h3-4,7-8,10-15,21-22,36H,2,5-6,9,16-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...				Bioorg Med Chem Lett 20: 5443-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.086 BindingDB Entry DOI: 10.7270/Q2J38SSG
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50325978 (CHEMBL1224387 | ethyl 4-(1-(4-(1-(4-fluorophenyl)-...) Show SMILES CCOC(=O)c1ccc(cc1O)C1CCN(CCCCc2nc3ccccc3n2-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C31H34FN3O3/c1-2-38-31(37)26-15-10-23(21-29(26)36)22-16-19-34(20-17-22)18-6-5-9-30-33-27-7-3-4-8-28(27)35(30)25-13-11-24(32)12-14-25/h3-4,7-8,10-15,21-22,36H,2,5-6,9,16-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 5443-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.086 BindingDB Entry DOI: 10.7270/Q2J38SSG
					More data for this Ligand-Target Pair