BDBM50325990 Aloisine B::CHEMBL1240969

SMILES: CC(C)c1c([nH]c2ccccc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=RJCSVKWAOJXHLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human))	BDBM50325990 (Aloisine B | CHEMBL1240969) Show SMILES CC(C)c1c([nH]c2ccccc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H16ClN/c1-11(2)16-14-5-3-4-6-15(14)19-17(16)12-7-9-13(18)10-8-12/h3-11,19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
The Rockefeller University Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclinB				Trends Pharmacol Sci 25: 471-80 (2004) Article DOI: 10.1016/j.tips.2004.07.006 BindingDB Entry DOI: 10.7270/Q2VX0HG5
					More data for this Ligand-Target Pair