null

SMILES: O=C1\C(=C\c2ccccc2)C(NC2CCCCC2)c2ccccc12

InChI Key: InChIKey=XJDKPLZUXCIMIS-HMMYKYKNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein phosphatase 6 (Homo sapiens (Human))	BDBM50326052 ((E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-...) Show SMILES O=C1\C(=C\c2ccccc2)C(NC2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of Myc-tagged human Dusp6 expressed in TPA-induced human HeLa cells asssessed as decrease in dephosphorylation of pERK measured by immunos...				Nat Chem Biol 5: 680-7 (2009) Article DOI: 10.1038/nchembio.190 BindingDB Entry DOI: 10.7270/Q2TD9XKD
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Homo sapiens (Human))	BDBM50326052 ((E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-...) Show SMILES O=C1\C(=C\c2ccccc2)C(NC2CCCCC2)c2ccccc12 Show InChI InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of Myc-tagged human Dusp1 expressed in TPA-induced human HeLa cells asssessed as decrease in dephosphorylation of pERK measured by immunos...				Nat Chem Biol 5: 680-7 (2009) Article DOI: 10.1038/nchembio.190 BindingDB Entry DOI: 10.7270/Q2TD9XKD
					More data for this Ligand-Target Pair