BDBM50326121 CHEMBL1242520::{5-[3-(4-Chloro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-yl]-4-methyl-thiazol-2-yl}-carbamic acid ethyl ester

SMILES: CCOC(=O)Nc1nc(C)c(s1)-c1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=XPXJVVOSWOEDEI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor Jun (Homo sapiens (Human))	BDBM50326121 (CHEMBL1242520 | {5-[3-(4-Chloro-phenyl)-4-oxo-3,4-...) Show SMILES CCOC(=O)Nc1nc(C)c(s1)-c1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H17ClN4O3S/c1-3-29-21(28)25-20-23-12(2)17(30-20)18-24-16-7-5-4-6-15(16)19(27)26(18)14-10-8-13(22)9-11-14/h4-11H,3H2,1-2H3,(H,23,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL					Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l...				Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW
					More data for this Ligand-Target Pair