BDBM50326122 3-(4-Chloro-phenyl)-2-(2-methylamino-4-phenyl-thiazol-5-yl)-3H-quinazolin-4-one::CHEMBL1242795

SMILES: CNc1nc(c(s1)-c1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1)-c1ccccc1

InChI Key: InChIKey=QIZVDVOITXXPLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50326122 (3-(4-Chloro-phenyl)-2-(2-methylamino-4-phenyl-thia...) Show SMILES CNc1nc(c(s1)-c1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1)-c1ccccc1 Show InChI InChI=1S/C24H17ClN4OS/c1-26-24-28-20(15-7-3-2-4-8-15)21(31-24)22-27-19-10-6-5-9-18(19)23(30)29(22)17-13-11-16(25)12-14-17/h2-14H,1H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL					Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l...				Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW
					More data for this Ligand-Target Pair