BDBM50326123 3-(4-Chloro-phenyl)-2-[2-(4-chloro-phenylamino)-4-phenyl-thiazol-5-yl]-3H-quinazolin-4-one::CHEMBL1241534

SMILES: Clc1ccc(Nc2nc(c(s2)-c2nc3ccccc3c(=O)n2-c2ccc(Cl)cc2)-c2ccccc2)cc1

InChI Key: InChIKey=WKFSZIHCDQMHOB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50326123 (3-(4-Chloro-phenyl)-2-[2-(4-chloro-phenylamino)-4-...) Show SMILES Clc1ccc(Nc2nc(c(s2)-c2nc3ccccc3c(=O)n2-c2ccc(Cl)cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H18Cl2N4OS/c30-19-10-14-21(15-11-19)32-29-34-25(18-6-2-1-3-7-18)26(37-29)27-33-24-9-5-4-8-23(24)28(36)35(27)22-16-12-20(31)13-17-22/h1-17H,(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
B. V. Patel Pharmaceutical Education and Research Development Centre Curated by ChEMBL					Assay Description Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by l...				Eur J Med Chem 45: 3558-63 (2010) Article DOI: 10.1016/j.ejmech.2010.04.038 BindingDB Entry DOI: 10.7270/Q2NP24MW
					More data for this Ligand-Target Pair