BDBM50326160 8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phenyl)thiazol-4-yl]dibenzo[b,d]furan-4-carboxylic acid::CHEMBL1241314

SMILES: OC(=O)[C@@H](Cc1ccccc1)C(=O)c1c(Br)cc(cc1Br)-c1nc(cs1)-c1ccc2oc3c(cccc3c2c1)C(O)=O

InChI Key: InChIKey=GNHGGGIKJQDMFD-QFIPXVFZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50326160 (8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...) Show SMILES OC(=O)[C@@H](Cc1ccccc1)C(=O)c1c(Br)cc(cc1Br)-c1nc(cs1)-c1ccc2oc3c(cccc3c2c1)C(O)=O |r| Show InChI InChI=1S/C32H19Br2NO6S/c33-23-13-18(14-24(34)27(23)28(36)22(32(39)40)11-16-5-2-1-3-6-16)30-35-25(15-42-30)17-9-10-26-21(12-17)19-7-4-8-20(31(37)38)29(19)41-26/h1-10,12-15,22H,11H2,(H,37,38)(H,39,40)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50326160 (8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...) Show SMILES OC(=O)[C@@H](Cc1ccccc1)C(=O)c1c(Br)cc(cc1Br)-c1nc(cs1)-c1ccc2oc3c(cccc3c2c1)C(O)=O |r| Show InChI InChI=1S/C32H19Br2NO6S/c33-23-13-18(14-24(34)27(23)28(36)22(32(39)40)11-16-5-2-1-3-6-16)30-35-25(15-42-30)17-9-10-26-21(12-17)19-7-4-8-20(31(37)38)29(19)41-26/h1-10,12-15,22H,11H2,(H,37,38)(H,39,40)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant LAR after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50326160 (8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...) Show SMILES OC(=O)[C@@H](Cc1ccccc1)C(=O)c1c(Br)cc(cc1Br)-c1nc(cs1)-c1ccc2oc3c(cccc3c2c1)C(O)=O |r| Show InChI InChI=1S/C32H19Br2NO6S/c33-23-13-18(14-24(34)27(23)28(36)22(32(39)40)11-16-5-2-1-3-6-16)30-35-25(15-42-30)17-9-10-26-21(12-17)19-7-4-8-20(31(37)38)29(19)41-26/h1-10,12-15,22H,11H2,(H,37,38)(H,39,40)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Center Curated by ChEMBL					Assay Description Inhibition of human recombinant TCPTP after 30 mins by spectrophotometry				Eur J Med Chem 45: 3709-18 (2010) Article DOI: 10.1016/j.ejmech.2010.05.020 BindingDB Entry DOI: 10.7270/Q24Q7V6S
					More data for this Ligand-Target Pair