BDBM50326220 CHEMBL1243233::N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propyl]-piperidin-4-yl}-isobutyramide

SMILES: CC(C)C(=O)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1

InChI Key: InChIKey=GIOXUGQDHRDESE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50326220 (CHEMBL1243233 | N-{1-[3-(3-Oxo-2,3-dihydro-benzo[1...) Show SMILES CC(C)C(=O)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1 Show InChI InChI=1S/C20H29N3O3/c1-15(2)20(25)21-16-8-12-22(13-9-16)10-5-11-23-17-6-3-4-7-18(17)26-14-19(23)24/h3-4,6-7,15-16H,5,8-14H2,1-2H3,(H,21,25)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay				J Med Chem 53: 6386-97 (2010) Article DOI: 10.1021/jm100697g BindingDB Entry DOI: 10.7270/Q2765G9K
					More data for this Ligand-Target Pair