BDBM50326239 CHEMBL1243110::N-{1-[3-(2-Oxo-3,4-dihydro-2H-quinolin-1-yl)-propyl]-piperidin-4-yl}-2-phenylacetamide

SMILES: O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)CCc3ccccc23)CC1

InChI Key: InChIKey=WTYOMTRDNXHOHC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50326239 (CHEMBL1243110 | N-{1-[3-(2-Oxo-3,4-dihydro-2H-quin...) Show SMILES O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)CCc3ccccc23)CC1 Show InChI InChI=1S/C25H31N3O2/c29-24(19-20-7-2-1-3-8-20)26-22-13-17-27(18-14-22)15-6-16-28-23-10-5-4-9-21(23)11-12-25(28)30/h1-5,7-10,22H,6,11-19H2,(H,26,29)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay				J Med Chem 53: 6386-97 (2010) Article DOI: 10.1021/jm100697g BindingDB Entry DOI: 10.7270/Q2765G9K
					More data for this Ligand-Target Pair