BDBM50326242 CHEMBL1243168::N-Methyl-N-{1-[3-(3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propyl]-piperidin-4-yl}-2-phenyl-acetamide

SMILES: CN(C1CCN(CCCN2C(=O)COc3ccccc23)CC1)C(=O)Cc1ccccc1

InChI Key: InChIKey=JRLRPPKTYBXZTF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50326242 (CHEMBL1243168 | N-Methyl-N-{1-[3-(3-oxo-2,3-dihydr...) Show SMILES CN(C1CCN(CCCN2C(=O)COc3ccccc23)CC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C25H31N3O3/c1-26(24(29)18-20-8-3-2-4-9-20)21-12-16-27(17-13-21)14-7-15-28-22-10-5-6-11-23(22)31-19-25(28)30/h2-6,8-11,21H,7,12-19H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay				J Med Chem 53: 6386-97 (2010) Article DOI: 10.1021/jm100697g BindingDB Entry DOI: 10.7270/Q2765G9K
					More data for this Ligand-Target Pair