BDBM50326384 (2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile::CHEMBL1243028

SMILES: Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=HAUFVTOXNBPOCA-SNRMKQJTSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50326384 ((2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C22H26FN5O3/c23-16-3-5-17(6-4-16)26-8-10-27(11-9-26)20(29)13-15-12-19(25-21(15)30)22(31)28-7-1-2-18(28)14-24/h3-6,15,18-19H,1-2,7-13H2,(H,25,30)/t15-,18-,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant FAP expressed in Hi5 insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50326384 ((2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C22H26FN5O3/c23-16-3-5-17(6-4-16)26-8-10-27(11-9-26)20(29)13-15-12-19(25-21(15)30)22(31)28-7-1-2-18(28)14-24/h3-6,15,18-19H,1-2,7-13H2,(H,25,30)/t15-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP8 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50326384 ((2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C22H26FN5O3/c23-16-3-5-17(6-4-16)26-8-10-27(11-9-26)20(29)13-15-12-19(25-21(15)30)22(31)28-7-1-2-18(28)14-24/h3-6,15,18-19H,1-2,7-13H2,(H,25,30)/t15-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP4 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50326384 ((2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C22H26FN5O3/c23-16-3-5-17(6-4-16)26-8-10-27(11-9-26)20(29)13-15-12-19(25-21(15)30)22(31)28-7-1-2-18(28)14-24/h3-6,15,18-19H,1-2,7-13H2,(H,25,30)/t15-,18-,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP2 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50326384 ((2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin...) Show SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)C[C@@H]1C[C@H](NC1=O)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C22H26FN5O3/c23-16-3-5-17(6-4-16)26-8-10-27(11-9-26)20(29)13-15-12-19(25-21(15)30)22(31)28-7-1-2-18(28)14-24/h3-6,15,18-19H,1-2,7-13H2,(H,25,30)/t15-,18-,19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged DPP9 expressed in insect cells				J Med Chem 53: 6572-83 (2010) Article DOI: 10.1021/jm1002556 BindingDB Entry DOI: 10.7270/Q23F4QM9
					More data for this Ligand-Target Pair