BDBM50326436 6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde::CHEMBL1240961

SMILES: Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12

InChI Key: InChIKey=IYKWFKKDLTZONH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50326436 (6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12 Show InChI InChI=1S/C15H9BrN2O/c16-11-2-1-3-12-13(11)10-5-4-9-8(7-19)6-17-14(9)15(10)18-12/h1-7,17-18H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Université Curated by ChEMBL					Assay Description Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins				Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50326436 (6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12 Show InChI InChI=1S/C15H9BrN2O/c16-11-2-1-3-12-13(11)10-5-4-9-8(7-19)6-17-14(9)15(10)18-12/h1-7,17-18H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Université Curated by ChEMBL					Assay Description Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins				Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50326436 (6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...) Show SMILES Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12 Show InChI InChI=1S/C15H9BrN2O/c16-11-2-1-3-12-13(11)10-5-4-9-8(7-19)6-17-14(9)15(10)18-12/h1-7,17-18H	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Clermont Université Curated by ChEMBL					Assay Description Inhibition of human GST fused Pim2 expressed in Escherichia coli after 30 mins				Bioorg Med Chem 18: 6865-73 (2010) Article DOI: 10.1016/j.bmc.2010.07.036 BindingDB Entry DOI: 10.7270/Q2PK0GBZ
					More data for this Ligand-Target Pair