BDBM50326770 4-isobutyl-5-methylene-2-oxo-1-(2,4,5-trichlorophenyl)-2,5-dihydro-1H-pyrrole-3-carbonitrile::CHEMBL1253938

SMILES: CC(C)CC1=C(C#N)C(=O)N(C1=C)c1cc(Cl)c(Cl)cc1Cl

InChI Key: InChIKey=NKKVUHPTHCADSY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ecdysone receptor (Lucilia cuprina)	BDBM50326770 (4-isobutyl-5-methylene-2-oxo-1-(2,4,5-trichlorophe...) Show SMILES CC(C)CC1=C(C#N)C(=O)N(C1=C)c1cc(Cl)c(Cl)cc1Cl |c:4| Show InChI InChI=1S/C16H13Cl3N2O/c1-8(2)4-10-9(3)21(16(22)11(10)7-20)15-6-13(18)12(17)5-14(15)19/h5-6,8H,3-4H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIRO Molecular and Health Technologies Curated by ChEMBL					Assay Description Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assay				Bioorg Med Chem 18: 5647-60 (2010) Article DOI: 10.1016/j.bmc.2010.06.020 BindingDB Entry DOI: 10.7270/Q2MK6D43
					More data for this Ligand-Target Pair