BDBM50326835 2-(2-Bromobenzyl)-6-methoxy-tetralone::CHEMBL1253946

SMILES: COc1ccc2C(=O)C(Cc3ccccc3Br)CCc2c1

InChI Key: InChIKey=GKGZPFKBDIIBHB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50326835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 24A1 (Homo sapiens (Human))	BDBM50326835 (2-(2-Bromobenzyl)-6-methoxy-tetralone | CHEMBL1253...) Show SMILES COc1ccc2C(=O)C(Cc3ccccc3Br)CCc2c1 Show InChI InChI=1S/C18H17BrO2/c1-21-15-8-9-16-12(11-15)6-7-14(18(16)20)10-13-4-2-3-5-17(13)19/h2-5,8-9,11,14H,6-7,10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP24A1 expressed in CHO cells				Eur J Med Chem 45: 4427-34 (2010) Article DOI: 10.1016/j.ejmech.2010.07.001 BindingDB Entry DOI: 10.7270/Q2ZW1M4W
					More data for this Ligand-Target Pair
Sterol 26-hydroxylase, mitochondrial (Homo sapiens (Human))	BDBM50326835 (2-(2-Bromobenzyl)-6-methoxy-tetralone | CHEMBL1253...) Show SMILES COc1ccc2C(=O)C(Cc3ccccc3Br)CCc2c1 Show InChI InChI=1S/C18H17BrO2/c1-21-15-8-9-16-12(11-15)6-7-14(18(16)20)10-13-4-2-3-5-17(13)19/h2-5,8-9,11,14H,6-7,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP27A1 expressed in CHO cells				Eur J Med Chem 45: 4427-34 (2010) Article DOI: 10.1016/j.ejmech.2010.07.001 BindingDB Entry DOI: 10.7270/Q2ZW1M4W
					More data for this Ligand-Target Pair