BDBM50327058 1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]-phenyl}-3-propylurea::CHEMBL1254591

SMILES: CCCNC(=O)Nc1ccc(Oc2ncnc3ccn(C)c23)cc1

InChI Key: InChIKey=ASKIKAANLSSJGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50327058 (1-{4-[(5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)ox...) Show SMILES CCCNC(=O)Nc1ccc(Oc2ncnc3ccn(C)c23)cc1 Show InChI InChI=1S/C17H19N5O2/c1-3-9-18-17(23)21-12-4-6-13(7-5-12)24-16-15-14(19-11-20-16)8-10-22(15)2/h4-8,10-11H,3,9H2,1-2H3,(H2,18,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem 18: 7260-73 (2010) Article DOI: 10.1016/j.bmc.2010.08.017 BindingDB Entry DOI: 10.7270/Q2NC61DC
					More data for this Ligand-Target Pair