BDBM50327186 5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)-N-(2-(diethylamino)ethyl)-2-methylbenzamide::CHEMBL1257450

SMILES: CCN(CC)CCNC(=O)c1cc(ccc1C)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key: InChIKey=UXWPTWPEVCXUAG-UHFFFAOYSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327186 (5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...) Show SMILES CCN(CC)CCNC(=O)c1cc(ccc1C)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C Show InChI InChI=1S/C32H40N6O2/c1-7-37(8-2)19-18-33-30(39)26-20-24(17-16-22(26)3)38-29(21-28(36-38)32(4,5)6)35-31(40)34-27-15-11-13-23-12-9-10-14-25(23)27/h9-17,20-21H,7-8,18-19H2,1-6H3,(H,33,39)(H2,34,35,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assay				Bioorg Med Chem Lett 20: 5787-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.097 BindingDB Entry DOI: 10.7270/Q2MC907J
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327186 (5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...) Show SMILES CCN(CC)CCNC(=O)c1cc(ccc1C)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C Show InChI InChI=1S/C32H40N6O2/c1-7-37(8-2)19-18-33-30(39)26-20-24(17-16-22(26)3)38-29(21-28(36-38)32(4,5)6)35-31(40)34-27-15-11-13-23-12-9-10-14-25(23)27/h9-17,20-21H,7-8,18-19H2,1-6H3,(H,33,39)(H2,34,35,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to full-length GST-tagged p38alpha by surface plasmon resonance assay				Bioorg Med Chem Lett 20: 5787-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.097 BindingDB Entry DOI: 10.7270/Q2MC907J
					More data for this Ligand-Target Pair