BDBM50327190 5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)-2-methyl-N-(3-(pyrrolidin-1-yl)propyl)benzamide::CHEMBL1258040

SMILES: Cc1ccc(cc1C(=O)NCCCN1CCCC1)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key: InChIKey=SCIXAOGWSHBJKV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327190 (5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...) Show SMILES Cc1ccc(cc1C(=O)NCCCN1CCCC1)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C Show InChI InChI=1S/C33H40N6O2/c1-23-15-16-25(21-27(23)31(40)34-17-10-20-38-18-7-8-19-38)39-30(22-29(37-39)33(2,3)4)36-32(41)35-28-14-9-12-24-11-5-6-13-26(24)28/h5-6,9,11-16,21-22H,7-8,10,17-20H2,1-4H3,(H,34,40)(H2,35,36,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	301	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assay				Bioorg Med Chem Lett 20: 5787-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.097 BindingDB Entry DOI: 10.7270/Q2MC907J
					More data for this Ligand-Target Pair