BDBM50327196 CHEMBL1258386::N-(2-aminoethyl)-5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)-N,2-dimethylbenzamide

SMILES: CN(CCN)C(=O)c1cc(ccc1C)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key: InChIKey=USAGNUHVPXEJPT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327196 (CHEMBL1258386 | N-(2-aminoethyl)-5-(3-tert-butyl-5...) Show SMILES CN(CCN)C(=O)c1cc(ccc1C)-n1nc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C Show InChI InChI=1S/C29H34N6O2/c1-19-13-14-21(17-23(19)27(36)34(5)16-15-30)35-26(18-25(33-35)29(2,3)4)32-28(37)31-24-12-8-10-20-9-6-7-11-22(20)24/h6-14,17-18H,15-16,30H2,1-5H3,(H2,31,32,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	715	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assay				Bioorg Med Chem Lett 20: 5787-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.097 BindingDB Entry DOI: 10.7270/Q2MC907J
					More data for this Ligand-Target Pair