BDBM50327205 5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)-N-(4-methoxyphenethyl)-2-methylbenzamide::CHEMBL1256043

SMILES: COc1ccc(CCNC(=O)c2cc(ccc2C)-n2nc(cc2NC(=O)Nc2cccc3ccccc23)C(C)(C)C)cc1

InChI Key: InChIKey=SSTHOCYSUQBPRR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327205   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327205 (5-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyr...) Show SMILES COc1ccc(CCNC(=O)c2cc(ccc2C)-n2nc(cc2NC(=O)Nc2cccc3ccccc23)C(C)(C)C)cc1 Show InChI InChI=1S/C35H37N5O3/c1-23-13-16-26(21-29(23)33(41)36-20-19-24-14-17-27(43-5)18-15-24)40-32(22-31(39-40)35(2,3)4)38-34(42)37-30-12-8-10-25-9-6-7-11-28(25)30/h6-18,21-22H,19-20H2,1-5H3,(H,36,41)(H2,37,38,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assay				Bioorg Med Chem Lett 20: 5787-92 (2010) Article DOI: 10.1016/j.bmcl.2010.04.097 BindingDB Entry DOI: 10.7270/Q2MC907J
					More data for this Ligand-Target Pair