BDBM50327254 CHEMBL1258166::endo-3-(8-(cyclopropylmethyl)-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES: NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3CC2CC2)c1

InChI Key: InChIKey=AQEIRYQRLMXQPR-SCAQPMJSSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50327254 (CHEMBL1258166 | endo-3-(8-(cyclopropylmethyl)-8-az...) Show SMILES NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3CC2CC2)c1 |r,TLB:17:16:9.15.10:13.12| Show InChI InChI=1S/C18H24N2O2/c19-18(21)13-2-1-3-16(8-13)22-17-9-14-6-7-15(10-17)20(14)11-12-4-5-12/h1-3,8,12,14-15,17H,4-7,9-11H2,(H2,19,21)/t14-,15+,17-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human delta opioid receptor assessed as inhibition of SNC80-stimulated [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50327254 (CHEMBL1258166 | endo-3-(8-(cyclopropylmethyl)-8-az...) Show SMILES NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3CC2CC2)c1 |r,TLB:17:16:9.15.10:13.12| Show InChI InChI=1S/C18H24N2O2/c19-18(21)13-2-1-3-16(8-13)22-17-9-14-6-7-15(10-17)20(14)11-12-4-5-12/h1-3,8,12,14-15,17H,4-7,9-11H2,(H2,19,21)/t14-,15+,17-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50327254 (CHEMBL1258166 | endo-3-(8-(cyclopropylmethyl)-8-az...) Show SMILES NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3CC2CC2)c1 |r,TLB:17:16:9.15.10:13.12| Show InChI InChI=1S/C18H24N2O2/c19-18(21)13-2-1-3-16(8-13)22-17-9-14-6-7-15(10-17)20(14)11-12-4-5-12/h1-3,8,12,14-15,17H,4-7,9-11H2,(H2,19,21)/t14-,15+,17-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50327254 (CHEMBL1258166 | endo-3-(8-(cyclopropylmethyl)-8-az...) Show SMILES NC(=O)c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3CC2CC2)c1 |r,TLB:17:16:9.15.10:13.12| Show InChI InChI=1S/C18H24N2O2/c19-18(21)13-2-1-3-16(8-13)22-17-9-14-6-7-15(10-17)20(14)11-12-4-5-12/h1-3,8,12,14-15,17H,4-7,9-11H2,(H2,19,21)/t14-,15+,17-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair