BDBM50327260 CHEMBL1258165::endo-3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES: CN1[C@H]2CC[C@@H]1C[C@H](C2)Oc1cccc(c1)C(N)=O

InChI Key: InChIKey=RLYMZSRJLRBKEY-DABQJJPHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50327260 (CHEMBL1258165 | endo-3-(8-methyl-8-azabicyclo[3.2....) Show SMILES CN1[C@H]2CC[C@@H]1C[C@H](C2)Oc1cccc(c1)C(N)=O |r,TLB:0:1:7.6.8:4.3| Show InChI InChI=1S/C15H20N2O2/c1-17-11-5-6-12(17)9-14(8-11)19-13-4-2-3-10(7-13)15(16)18/h2-4,7,11-12,14H,5-6,8-9H2,1H3,(H2,16,18)/t11-,12+,14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>33	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50327260 (CHEMBL1258165 | endo-3-(8-methyl-8-azabicyclo[3.2....) Show SMILES CN1[C@H]2CC[C@@H]1C[C@H](C2)Oc1cccc(c1)C(N)=O |r,TLB:0:1:7.6.8:4.3| Show InChI InChI=1S/C15H20N2O2/c1-17-11-5-6-12(17)9-14(8-11)19-13-4-2-3-10(7-13)15(16)18/h2-4,7,11-12,14H,5-6,8-9H2,1H3,(H2,16,18)/t11-,12+,14-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
					More data for this Ligand-Target Pair