BDBM50327409 (S)-N-sec-butyl-5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-yl)thiazol-2-amine::CHEMBL1258741

SMILES: CC[C@H](C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl

InChI Key: InChIKey=STSWOANFFVWUHF-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327409 ((S)-N-sec-butyl-5-(6-(2-chlorophenyl)-2-(pyridin-2...) Show SMILES CC[C@H](C)Nc1ncc(s1)-c1cc(nc(n1)-c1ccccn1)-c1ccccc1Cl |r| Show InChI InChI=1S/C22H20ClN5S/c1-3-14(2)26-22-25-13-20(29-22)19-12-18(15-8-4-5-9-16(15)23)27-21(28-19)17-10-6-7-11-24-17/h4-14H,3H2,1-2H3,(H,25,26)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair