BDBM50327414 2-(4-(2-chlorophenyl)-6-(2-(isopropylamino)thiazol-5-yl)pyrimidin-2-ylamino)ethanol::CHEMBL1258977

SMILES: CC(C)Nc1ncc(s1)-c1cc(nc(NCCO)n1)-c1ccccc1Cl

InChI Key: InChIKey=CZCSZRYNOSGEEF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50327414 (2-(4-(2-chlorophenyl)-6-(2-(isopropylamino)thiazol...) Show SMILES CC(C)Nc1ncc(s1)-c1cc(nc(NCCO)n1)-c1ccccc1Cl Show InChI InChI=1S/C18H20ClN5OS/c1-11(2)22-18-21-10-16(26-18)15-9-14(12-5-3-4-6-13(12)19)23-17(24-15)20-7-8-25/h3-6,9-11,25H,7-8H2,1-2H3,(H,21,22)(H,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation counting				Bioorg Med Chem Lett 20: 5864-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.102 BindingDB Entry DOI: 10.7270/Q22F7NP6
					More data for this Ligand-Target Pair