null
SMILES: CC(=O)N1N=C(CC1c1ccc(O)cc1)c1cc2c(Br)cccc2oc1=O
InChI Key: InChIKey=HLMDFDICHJSNAA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Telomerase reverse transcriptase (Homo sapiens (Human)) | BDBM50327443 (3-(1-acetyl-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyr...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui University of Technology Curated by ChEMBL | Assay Description Inhibition of telomerase in human SGC7901 cells by TRAP assay | Bioorg Med Chem Lett 20: 5705-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.017 BindingDB Entry DOI: 10.7270/Q2P84C30 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase I, thermostable (Thermus aquaticus) | BDBM50327443 (3-(1-acetyl-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyr...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Anhui University of Technology Curated by ChEMBL | Assay Description Inhibition of Taq polymerase | Bioorg Med Chem Lett 20: 5705-8 (2010) Article DOI: 10.1016/j.bmcl.2010.08.017 BindingDB Entry DOI: 10.7270/Q2P84C30 | |||||||||||
More data for this Ligand-Target Pair |